In this investment guide, you will find all physically-backed ETNs that allow you to invest in a cryptocurrency. Performance of cryptocurrencies in comparison. We've factored this into our consideration, but there are other reasons why a digital token may be included in the list, as well. Ethereum (ETH) Litecoin (LTC) Cardano (ADA) Polkadot (DOT) Bitcoin Cash (BCH) Stellar (XLM) Chainlink. Binance Coin (BNB). Which are the three biggest cryptocurrencies? Bitcoin, the best-known and first major cryptocurrency, launched in and remains the market leader. Its market.